3d GUI
Trying to somehow utilize 3d acceleration to make GUIs better has been around for a while, but here’s someone who has made what I think is particularly good use of it. http://www.marcmoini.com/f3_en.html shows an apple macintosh desktop in a perspective so that it appears to be laid out in front of you (like an actual desktop) with more commonly used shortcuts up front (appearing larger) and lesser used ones in the back (appearing smaller).
I think I’ll adopt something similar if I ever get around to building a GUI.